Diabetes mellitus: Women are at higher risk of venous thromboembolism than men


Jan 3, 2023

A research team from the Complexity Science Hub and MedUni Vienna analyzed 180,034 patients with diabetes mellitus and found evidence that women are at higher risk of venous thromboembolism than men – particularly during perimenopause. In total, massive amounts of data from around 45 million hospitalizations and 7,239,710 patients in Austria between 2003 and 2014 were studied.  

 

 

“Our analyses show for the first time that diabetes mellitus might be associated with venous thromboembolism (VTE) to a greater extent in women than in men,” explains Elma Dervic from the Complexity Science Hub. The risk of women with diabetes mellitus (DM) also suffering from VTE is 1.52 times higher than for women without DM. For men, on the contrast, the risk is only 1.3 times higher.

 

“After the age of 40 in particular, the relative risk of VTE increases,” explains Carola Deischinger from the Medical University of Vienna. The effect peaks in women between 50 and 59 years of age, where the risk is 1.65 times higher, according to the results of the study published in Diabetes Research and Clinical Practice.

 

AROUND 45 MILLION DATA FROM AUSTRIA

 

To determine the gender-specific impact of diabetes mellitus on the risk of VTE, the team examined a population-based dataset. “With around 45 million data records, it covers all inpatient stays in Austria between 2003 and 2014,” says Dervic. Of the 180,034 patients with DM, 70,739 were female and 109,295 were male.

 

 

New study on Diabetes mellitus: Women are at higher risk of venous thromboembolism than men © CSH Vienna & MedUni Vienna

 

 

DIABETES MELLITUS: A KNOWN RISK FACTOR FOR VTE

 

Venous thromboembolism (VTE) includes two clinical pictures: deep vein thrombosis and pulmonary artery embolism, the latter being a dangerous complication of thrombosis. “Typically, the risk of developing venous thromboembolism (VTE) is about the same in both sexes,” Deischinger explains. Diabetes mellitus, a chronic disease that affects over eight percent of the world’s population, is known to be a risk factor for VTE. “In our study, we again found a 1.4 times higher risk of VTE in patients with diabetes mellitus than in the control group without diabetes mellitus,” says Dervic.

 

 

New study on Diabetes mellitus at Complexity Science Hub: Women are at higher risk of venous thromboembolism than men © Shutterstock

 

 

GENDER DIFFERENCES IN MEDICINE

 

What is new is the gender aspect. While traditional treatment methods could only take little account of gender-specific differences in numerous diseases, “thanks to great research efforts and Big Data analyses, we already know much more about this today”, says Dervic. As a result, these differences can be analyzed in detail and treatments can be adjusted accordingly. This study was preceded by two other studies dealing with the gender-specific differences of patients with diabetes mellitus on the expression of depression on the one hand and Parkinson’s disease on the other. Here, too, significant gender specific differences were found.

 

IMPORTANT STEP TOWARDS PREVENTION

 

“Our findings suggest that women with diabetes mellitus should be monitored more carefully for the development of VTE, especially during their perimenopause,” emphasizes Alexandra Kautzky-Willer from MedUni Vienna and last author of the study. This shows once again that the biological advantage of women – especially for vascular complications in the case of diabetes – is dwindling and their risk increases further with the drop in estrogen in the menopause. Even more reason for intensive treatment of all risk factors at a younger age.

 

To be able to record this gender-specific correlation between DM and VTE in even greater detail, analyses are needed that investigate the causes of the relative increase in risk. “This would be an important step towards the prevention of VTE in patients with DM, especially if they are women,” says Dervic.

 

 

The study “Diabetes mellitus is associated with a higher relative risk for venous thromboembolism in females than in males” has been published in Diabetes Research and Clinical Practice.


Research News

Jan 23, 2023

Predicting human group sizes with physics

Spotlight

Jan 20, 2023

CSH-STATEMENT | New methods for investigating child pornography

Event

Pressemeeting: Erste Ergebnisse zur Bekämpfung von Cyberkriminalität


Jan 31, 2023 | 16:3017:30

Complexity Science Hub Vienna

Publication

W. Schueller, J. Wachs, V. D. P. Servedio, S. Thurner, V. Loreto

Evolving collaboration, dependencies, and use in the Rust Open Source Software ecosystem

Scientific Data 9 (2022) 703

Publication

N. Pontika, T. Klebel, A. Correia, H. Metzler, P. Knoth, T. Ross-Hellauer

Indicators of research quality, quantity, openness and responsibility in institutional review, promotion and tenure policies across seven countries

Quantitative Science Studies 1-49

Press

Staatsanwälte jagen mit Datenforschern Cyberkriminelle [feat.Bernhard Haslhofer]


Salzburger Nachrichten, Jan 27, 2023

Event

An Evening with Art & Science at the Hub: Autophagic landscapes: on the paradox of survival through self-degradation by Ayelen Valko & Dorotea Fracchiolla


Jan 27, 2023 | 18:0022:00

Complexity Science Hub Vienna

Research News

Jan 24, 2023

Berlin could produce more than 80% of its fresh vegetables locally

Press

Arzneimittelengpass in Österreich [feat.Peter Klimek]


Ö1 / Morgenjournal, Jan 24, 2023

Publication

V.D.P. Servedio, M. R. Ferreira, N. Reisz, R. Costas, S. Thurner

Scale-free growth in regional scientific capacity building explains long-term scientific dominance

Chaos, Solitons & Fractals 167 (2023) 113020

Press

Totes Netz [feat.Christian Diem]


Ö1 Dimensionen, Jan 24, 2023

Event

CSH Talk by Lioba Heimbach: Front-running in Decentralized Finance and Possible Solutions


Jan 27, 2023 | 15:0016:00

Complexity Science Hub Vienna

Research News

Jan 23, 2023

Predicting human group sizes with physics

Spotlight

Jan 20, 2023

CSH-STATEMENT | New methods for investigating child pornography

Event

Pressemeeting: Erste Ergebnisse zur Bekämpfung von Cyberkriminalität


Jan 31, 2023 | 16:3017:30

Complexity Science Hub Vienna

Publication

W. Schueller, J. Wachs, V. D. P. Servedio, S. Thurner, V. Loreto

Evolving collaboration, dependencies, and use in the Rust Open Source Software ecosystem

Scientific Data 9 (2022) 703

Publication

N. Pontika, T. Klebel, A. Correia, H. Metzler, P. Knoth, T. Ross-Hellauer

Indicators of research quality, quantity, openness and responsibility in institutional review, promotion and tenure policies across seven countries

Quantitative Science Studies 1-49

Press

Staatsanwälte jagen mit Datenforschern Cyberkriminelle [feat.Bernhard Haslhofer]


Salzburger Nachrichten, Jan 27, 2023

Event

An Evening with Art & Science at the Hub: Autophagic landscapes: on the paradox of survival through self-degradation by Ayelen Valko & Dorotea Fracchiolla


Jan 27, 2023 | 18:0022:00

Complexity Science Hub Vienna

Research News

Jan 24, 2023

Berlin could produce more than 80% of its fresh vegetables locally

Press

Arzneimittelengpass in Österreich [feat.Peter Klimek]


Ö1 / Morgenjournal, Jan 24, 2023

Publication

V.D.P. Servedio, M. R. Ferreira, N. Reisz, R. Costas, S. Thurner

Scale-free growth in regional scientific capacity building explains long-term scientific dominance

Chaos, Solitons & Fractals 167 (2023) 113020

Press

Totes Netz [feat.Christian Diem]


Ö1 Dimensionen, Jan 24, 2023

Event

CSH Talk by Lioba Heimbach: Front-running in Decentralized Finance and Possible Solutions


Jan 27, 2023 | 15:0016:00

Complexity Science Hub Vienna

Research News

Jan 24, 2023

Berlin could produce more than 80% of its fresh vegetables locally

Spotlight

Jan 20, 2023

CSH-STATEMENT | New methods for investigating child pornography

Research News

Jan 23, 2023

Predicting human group sizes with physics

Research News

Jan 19, 2023

Simply explained: Decentralized Finance, Blockchains and smart contracts

News

Jan 16, 2023

CSH Winter School is off to a great start

Spotlight

Jan 11, 2023

Explore the world's supply chains

Research News

Jan 3, 2023

Diabetes mellitus: Women are at higher risk of venous thromboembolism than men

Research News

Dec 28, 2022

NO CRITICAL MASS OF SCIENTISTS: TRY TO BE A PIONEER

Research News

Dec 19, 2022

Of mice and men

Research News

Dec 14, 2022

Tweets can prevent suicides

Press

Staatsanwälte jagen mit Datenforschern Cyberkriminelle [feat.Bernhard Haslhofer]


Salzburger Nachrichten, Jan 27, 2023

Press

Totes Netz [feat.Christian Diem]


Ö1 Dimensionen, Jan 24, 2023

Press

Arzneimittelengpass in Österreich [feat.Peter Klimek]


Ö1 / Morgenjournal, Jan 24, 2023

Press

Stoppt den Kindesmissbrauch [feat.Bernhard Haslhofer]


ORF 2 / Thema, Jan 24, 2023

Press

Menschen verhalten sich wie Teilchen mit Spin [feat.Stefan Thurner, Jan Korbel]


APA-Science, Jan 23, 2023

Press

Infographie. Quels sont les animaux malades du Covid? [French] [feat.Amélie Desvars-Larrive]


Courrier International, Jan 21, 2023

Press

Ökonomische Netzwerke durchschauen [feat.Matthias Raddant]


upgrade (46-49), Jan 11, 2023

Press

Wie der Kreml geflohene Russen drangsaliert [feat.Johannes Wachs]


Handelsblatt, Jan 20, 2023

Press

Код на исходе [Russian][feat. Johannes Wachs]


Novaya Gazeta Europe, Jan 11, 2023

Press

So machen wir den Markt kaputt [feat.Stefan Thurner]


Die Presse, Jan 8, 2023

Publication

V.D.P. Servedio, M. R. Ferreira, N. Reisz, R. Costas, S. Thurner

Scale-free growth in regional scientific capacity building explains long-term scientific dominance

Chaos, Solitons & Fractals 167 (2023) 113020

Publication

M. Leutner, M. Butylina, C. Matzhold, et al.

Simvastatin therapy in higher dosages deteriorates bone quality: Consistent evidence from population-wide patient data and interventional mouse studies

Biomedicine & Pharmacotherapy 158 (2023) 114089

Publication

W. Schueller, J. Wachs, V. D. P. Servedio, S. Thurner, V. Loreto

Evolving collaboration, dependencies, and use in the Rust Open Source Software ecosystem

Scientific Data 9 (2022) 703

Publication

N. Pontika, T. Klebel, A. Correia, H. Metzler, P. Knoth, T. Ross-Hellauer

Indicators of research quality, quantity, openness and responsibility in institutional review, promotion and tenure policies across seven countries

Quantitative Science Studies 1-49

Publication

H. Kong, S. Martin-Gutierrez, F. Karimi

Influence of the first-mover advantage on the gender disparities in physics citations

Communications Physics 5 (243) (2022)

Publication

A. Pichler, M. Pangallo, M. del Rio-Chanona, F. Lafond, D. Farmer

Forecasting the propagation of pandemic shocks with a dynamic input-output model

Journal of Economic Dynamics and Control (2022) 104527

Publication

J. Lasser, S. Taofeek Aroyehun, et al.

Social media sharing of low quality news sources by political elites

PNAS Nexus (2022) pgac186

Publication

R. Prieto Curiel, A. Schumann, I. Heo, P. Heinrigs

Detecting cities with high intermediacy in the African urban network

Computers, Environment and Urban Systems 98 (2022) 101869

Publication

T. Reisch, G. Heiler, C. Diem, P. Klimek, S. Thurner

Monitoring supply networks from mobile phone data for estimating the systemic risk of an economy

Scientific Reports 12 (13347) (2022)

Publication

G. De Marzo, F. Pandolfelli, V.D.P. Servedio

Modeling innovation in the cryptocurrency ecosystem

Scientific Reports 12 (12942) (2022)

Publication

A. Nerpel, et al.

SARS-ANI: a global open access dataset of reported SARS-CoV-2 events in animals

Scientific Data 9 (438) (2022)

Publication

M. Kaleta, J. Lasser, E. Dervic, et al.

Stress-testing the resilience of the Austrian healthcare system using agent-based simulation

Nature Communications 13 (4259) (2022)

Event

CSH Talk by Lioba Heimbach: Front-running in Decentralized Finance and Possible Solutions


Jan 27, 2023 | 15:0016:00

Complexity Science Hub Vienna

Event

An Evening with Art & Science at the Hub: Autophagic landscapes: on the paradox of survival through self-degradation by Ayelen Valko & Dorotea Fracchiolla


Jan 27, 2023 | 18:0022:00

Complexity Science Hub Vienna

Event

Pressemeeting: Erste Ergebnisse zur Bekämpfung von Cyberkriminalität


Jan 31, 2023 | 16:3017:30

Complexity Science Hub Vienna

Event

CSH Talk by Sandor Juhasz: "Amenity complexity and the diversity of visitors in cities"


Feb 03, 2023 | 15:0016:00

Complexity Science Hub Vienna